GPCR signaling in cardiovascular research addressed with HTRF second messenger assays

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See how peer researchers monitor GPCR signaling with HTRF

This literature review illustrates the possibilities of GPCR monitoring with HTRF second messenger cAMP and IP-1 assays in a cardiovascular context. It features experiments and data from published studies that investigated b-arrestin-biased ligands of the angiotensin II and apelin receptors, as well as inhibitor screening of the relaxin receptor and atrial natriuretic peptide signaling through ANPRs.

Features

  • Review the GPCRs involved in cardiovascular function
  • Biased ligand investigation, GPCR inhibitor screening and ANPR signaling studies
  • Data from published scientific literature