GPCR signaling in cardiovascular research addressed with HTRF second messenger assays

See how peer researchers monitor GPCR signaling with HTRF

This literature review illustrates the possibilities of GPCR monitoring with HTRF second messenger cAMP and IP-1 assays in a cardiovascular context. It features experiments and data from published studies that investigated b-arrestin-biased ligands of the angiotensin II and apelin receptors, as well as inhibitor screening of the relaxin receptor and atrial natriuretic peptide signaling through ANPRs.

Features

  • Review the GPCRs involved in cardiovascular function
  • Biased ligand investigation, GPCR inhibitor screening and ANPR signaling studies
  • Data from published scientific literature