4 cellular models: a single GPCR monitoring approach
ERK1/2 phosphorylation is part of a larger GPCR mediated pathway. This Application Note shows how you can investigate GPCR stimulation by pharmacological compounds in a range of cellular models of varying complexity. The data provided demonstrate the sensitivity of such assays for studying the downstream effects of compounds, as well as explaining the possibility of miniaturizing experiments for High Throughput Screening.
Features
Assay principle
Materials and methods for the experiments
Results showing the relevance of this approach for stable lines, and immortalized, cancer and tumor patient-derived cells.
Download Application note
We are committed to your privacy. Revvity needs the contact information you provide us to keep you aware about relevant content, products, and services. You may unsubscribe from these communications at any time. For more information check out our Privacy Policy.
